17-Hydroxycortiosteroids Urine Test

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Latest Edit: Hector 2014-03-21 (EDT)

See Also Lab Tests

17-Hydroxycorticosteroids urine test is used to assess adrenocortical function by measuring the cortisol metabolites (17-OCHS) in a 24-hour urine collection.[1]


  • Elevated levels of 17-hydroxycortiosteroids occur with adrenal hyperfunction (Cushing syndrome), whether the condition is caused by a pituitary or adrenal tumor, bilateral adrenal hyperplasia, or ectopic tumors producing adrenocorticotropic hormone (ACTH)

Patient Preparation

  • No fasting required.
  • 24-hour urine sample, discard the first morning urine sample
  • Factors which can cause increased levels
  • Factors which can cause decreased levels
  • Medications such as estrogen, oral contraceptives, phenothiazides, and reserpine.

Clinical Implications

High levels indicate:

Low levels indicate:

Associated Tests


  1. Pagana Kathleen D, Pagana Timothy J (2006) Mosby's Manual of Diagnostic and Laboratory Tests, Mosby.