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Latest Edit: Hector 2014-03-24 (EDT)

See Also Lab Tests

Fibrinogen is an acute-phase reactant protein that is produced by the liver. It is an important component of the "common pathway" in the coagulation system. During a coagulation process, fibrinogen is converted to fibrin by the action of thrombin.[1],[2]


Patient Preparation

  • No fasting is required.
  • Factors which can cause increased levels:
  • Drugs: estrogens and oral contraceptives
  • Factors which can cause decreased levels:
  • Fibrinolysins
  • Drugs: anabolic steroids, androgens, asparaginase, phenobarbital, streptokinase, urokinase, and valproic acid.

Clinical Implications

High levels indicate:

Low levels indicate:

Associated Tests


  1. Pagana Kathleen D, Pagana Timothy J (1998) Mosby's Manual of Diagnostic and Laboratory Tests, Mosby, Inc
  2. Weatherby Dicken, Ferguson Scott (2002) Blood Chemistry and CBC Analysis: Clinical Laboratory Testing from a Functional Perspective, Bear Mountain