Prostate Specific Antigen (PSA)
|See Also||Lab Tests|
Prostate specific antigen or PSA is a glycoprotein (part carbohydrate, part protein) found in the cytoplasm of prostatic epithelial cells. Although this antigen can be detected in all males, the levels of PSA are greatly increased in patients with prostate cancer.
|Article||Interpreting and Using the PSA Test,2010 November NDNR|
- This test is used as a screening method for early detection of prostatic cancer and to monitor the disease after treatment.
- PSA and prostatic acid phosphatase or PAP levels can be found to be minimally elevated in patients with benign prostatic hypertrophy (BPH) and prostatitis
- No fasting is required
- Factors which can cause increased levels:
- Rectal examinations, prostatic manipulation by biopsy or transurethral resection of the prostate (TURP)
- Factors which can cause decreased levels:
- None noted
High levels indicate:
- Prostatic acid phosphatase (PAP), PSA ratio
- Pagana Kathleen D, Pagana Timothy J, (1998) Mosby's Manual of Diagnostic and Laboratory Tests, Mosby, Inc