VLDL
From Health Facts
Latest Edit: Hector 2014-03-21 (EDT)
See Also | Lab Tests |
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This test is part of the lipid profile, which is performed to identify persons at risk for developing heart disease as well as to monitor therapy if abnormalities are found.[1]
Discussion
- Lipoproteins are proteins in the blood that transport cholesterol, triglycerides, and other insoluble fats. They are grouped into chylomicrons, LDLs, VLDLs, and HDLs.
- VLDLs, or very-low-density lipoproteins are types of non-HDL, or non-high density lipoprotein cholesterol.
- Non-HDL cholesterol has been found to be a useful predictor of coronary outcomes.
Patient Preparation
- Fasting is required 12-14 hours before testing.
Clinical Implications
High levels indicate:
- Familial LDL lipoproteinemia
- Nephrotic syndrome
- Glycogen storage diseases
- Hypothyroidism
- Alcohol consumption
- Chronic liver disease (e.g. hepatitis, cirrhosis)
- Hepatoma
- Gammopathies
- Familial hypercholesterolemia type IIa
- Cushing syndrome
- Apoprotein CII deficiency
Low levels indicate:
- Familial hypolipoproteinemia
- Hypoproteinemia
- Hyperthyroidism
Associated Tests
References
- ↑ Pagana Kathleen D, Pagana Timothy J (2006) Mosby's Manual of Diagnostic and Laboratory Tests, Mosby.