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Latest Edit: Iva 2011-06-01 (EDT)

Some botanicals have an opposing of antagonistic action on drugs. For example, botanicals with a high affinity to scavenge free radicals might reduce the efficacy of other drugs.

In an antagonistic reaction you end up with the effect that 1 (drug) + 1 (herb) = 1 (effect) or 1 (drug) + 1 (herb) = 0 (no effect).