C-peptide
From Health Facts
Latest Edit: Hector 2014-03-24 (EDT)
| See Also | Lab Tests |
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The C-peptide test, also known as the insulin C-peptide test is used to monitor insulin production by the beta cells in the pancreas. This test can help to determine the cause of hypoglycemia.[1], [2]
Discussion
- This test measures the amount of C-peptide; a substance that is produced when proinsulin, an inactive molecule, splits apart to form C-peptide and insulin. C-peptide can be found in a blood or urine sample.
- C-peptide is produced at the same rate as insulin, thereby making it a useful marker of insulin production.
- This test may be used to help evaluate the production of insulin made by the body.
Patient Preparation
- Ask your doctor if fasting is required before having the test performed.
Clinical Implications
High levels indicate:
- High levels of endogenous insulin production
- Insulinoma
- Hypokalemia
- Pregnancy
- Cushing's syndrome
- Renal failure
Low levels indicate:
- Low levels of endogenous insulin production
- Suppression by exogenous insulin
Associated Tests
References
- ↑ Pagana Kathleen D, Pagana Timothy J (2006) Mosby's Manual of Diagnostic and Laboratory Tests, Mosby.
- ↑ Weatherby Dicken, Ferguson Scott (2002) Blood Chemistry and CBC Analysis: Clinical Laboratory Testing from a Functional Perspective, Bear Mountain.
