From Health Facts
Latest Edit: Hector 2014-03-24 (EDT)
|See Also||Lab Tests|
- CA-125 is a tumor marker with a high degree of sensitivity and specificity for ovarian cancer.
- Although this tumor marker cannot be used to diagnose ovarian cancer, it can help support the diagnosis of ovarian cancer and determine a patient's response to therapy.
- Comparative testing can show a progressive decline in CA-125 levels for patients responding to treatment.
- This test is not as effective at screening asymptomatic women due to its lack of specificity. Therefore it is mainly used in "high risk" women.
- No fasting required.
- Factors which can cause increased levels
- First trimester of pregnancy, normal menstruation, patients with benign peritoneal diseases (e.g. cirrhosis, endometriosis)
- Factors which can cause decreased levels
- None noted
High levels indicate:
- Malignant Disorders:
- Pagana Kathleen D, Pagana Timothy J (2006) Mosby's Manual of Diagnostic and Laboratory Tests, Mosby.
- Weatherby Dicken, Ferguson Scott (2002) Blood Chemistry and CBC Analysis: Clinical Laboratory Testing from a Functional Perspective, Bear Mountain.