CCNM Peer Reviewed Publications

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Latest Edit: General 2014-3-13 (EDT)

Peer reviewed publications of the Canadian College of Naturopathic Medicine.

Wu P, Wilson K, Dimoulas P, Mills EJ. Effectiveness of smoking cessation therapies: a systematic review & meta-analysis. BMC Public Health 2006;6:300 [1]
Mills EJ, Wu P, Gagnier J, Ebbert JO. Efficacy of acupuncture for cocaine dependence: a systematic review & meta-analysis. Harm Reduct J. 2005;2(1):4 [2]
Kennedy D, Lee T, Seely D. A comparative review of thermography as a breast cancer screening technique. Integrative Cancer Therapies 2009;8(1):9-16 [3]
Seely DM, Weeks LC, Young S. A systematic review of integrative oncology programs Current Oncology 2012 Dec;19(6):436-61 [4]
Leonard BJ, Kennedy DA, Cheng FC, Chang KK, Seely D, Mills E. An in vivo analysis of the herbal compound Essiac. Anticancer Research, 2006; 26(4B):3057-63. [5]
Dugoua JJ, Wu P, Seely D, Eyawo O, Mills E. Astralagus-containing Chinese herbal combinations for advanced non-small-cell lung cancer: A meta-analysis of 65 clinical trials enrolling 4,751 patients. Lung Cancer: Targets and Therapy 2010;1:85-100 [6]
Mills EJ, Seely D, Rachlis B, Griffith L, Wu P, Wilson K, Ellis P, Wright JR. Barriers to participation in clinical trials of cancer: a meta-analysis and systematic review of patient-reported factors. Lancet Oncology, 2006;7(2):141-8 [7]
Fritz H, Seely D, McGowan J, Skidmore B, Fernandes R, Kennedy DA, Cooley K, Wong R, Sagar S, Balneaves LG, Fergusson D. Black cohosh and breast cancer: a systematic review Integrative Cancer Therapy 2013 Feb 25 [8]
Weeks LC, Seely D, Balneaves LG, Boon HS, Leis A, Oneschuk D, Sagar SM, Verhoef MJ Canadian integrative oncology research priorities: results of a consensus-building process. Current Oncology 2013 Aug;20(4):289-99 [9]
Flower G, Fritz H, Balneaves LG, Verma S, Skidmore B, Fernandes R, Kennedy DA, Cooley K, Wong R, Sagar S, Fergusson D, Seely D Flax and breast cancer: a systematic review Integrative Cancer Therapy September 2013 [10]
Heidi Fritz, Dugald Seely, Deborah A. Kennedy, Rochelle Fernandes, Kieran Cooley and Dean Fergusson Green tea and lung cancer: a systematic review Integrative Cancer Therapy, April 2012 [11]
Seely D, Kennedy DA, Myers SP, Cheras PA, Lin D, Li R, Cattley T, Brent PA, Mills E, Leonard BJ. In vitro analysis of the herbal compound Essiac. Anticancer Research, 2007;27(6B):3875-82. [12]
Brazier AS, Balneaves LG, Seely D, Stephen JE, Suryaprakash N, Taylor-Brown JW. Integrative practices of Canadian oncology health professionals. Current Oncology, 2008 Aug;15 Suppl 2:s110.es87-91. [13]
Seely D, Wu P, Fritz H, Kennedy DA, Tsui T, Seely AJ, Mills E. Melatonin as adjuvant cancer care with and without chemotherapy: meta-analysis Integrative Cancer Therapy 2011 Oct 21 [14]
Mills E, Wu P, Seely D, Guyatt G. Melatonin in the treatment of cancer: a systematic review of randomized controlled trials and meta-analysis. Journal of Pineal Research 2005;39(4):360-6. [15]
Stempak D, Seely D, Baruchel S. Metronomic dosing of chemotherapy: applications in pediatric oncology. Cancer Invest. 2006;24(4):432-43. [16]
Balneaves LG, Weeks L, Seely D. Patient decision-making about complementary and alternative medicine in cancer. Current Oncology, 2008;15 Suppl 2:s94-s100.[17]
Fritz H, Kennedy D, Fergusson D, Fernandes R, Cooley K, Seely A, Sagar S, Wong R, Seely D Selenium and lung cancer: a systematic review and meta analysis PLoS ONE 6(11): e26259. doi:10.1371/journal.pone.0026259 [18]
Fritz H, Seely D, Flower G, Skidmore B, Fernandes R, Vadeboncoeur S, Kennedy DA, Cooley K, Wong R, Sagar S, Sabri E, Fergusson D Soy, Red Clover, and Isoflavones and Breast Cancer: A Systematic Review PLoS ONE 8(11): e81968. doi:10.1371/journal.pone.0081968 [19]
Seely D, Mills EJ, Wu P, Verma S, Guyatt GH. The effects of green tea consumption on incidence of breast cancer and of breast cancer: a systematic review. Integr Cancer Ther. 2005;4(2):144-55.[20]
Heidi Fritz , Deborah Kennedy , Dean Fergusson , Rochelle Fernandes , Steve Doucette , Kieran Cooley , Andrew Seely , Stephen Sagar , Raimond Wong , Dugald Seely Vitamin A and retinoid derivatives for lung cancer: a systematic review and meta analysis PLoS One 2011; 6(6): e21107 [21]
Kennedy DA, Cooley K, Skidmore B, Fritz H, Campbell T, Seely C Vitamin D: Pharmacokinetics and Safety When Used in Conjunction with the Pharmaceutical Drugs Used in Cancer Patients: A Systematic Review Cancers 2013, 5, 255-280 [22]
Seely D, Oneschuk D. Interactions of natural health products with biomedical cancer treatments. Current Oncology, 2008; 15 Suppl 2:s109.es81-10.es86. [23]
Seely D, Stempak D, Baruchel S. Strategy for controlling potential interactions between natural health products and chemotherapy. Journal Pediatric Hematol Oncol, 2007;29(1):32-47.


Wu P, Mills E, Moher D, Seely D. Acupuncture in Poststroke Rehabilitation - A Systematic Review and Meta-Analysis of Randomized Trials. Journal of the American Heart Association [25]
Seely DM, Wu P, Mills EJ. EDTA chelation therapy for cardiovascular disease: a systematic review. BMC Cardiovascular Disorders, 2005;5:32. [26]
Kanji S, Seely D, Yazdi F, Tetzlaff J, Singh K, Tsertsvadze A, Tricco AC, Sears ME, Ooi TC, Turek MA, Skidmore B, Ansari MT Interactions of commonly used dietary supplements with cardiovascular drugs: a systematic review Syst Rev. 2012 May 31;1:26 [27]
Seely D, Szczurko O, Cooley K, Fritz H, Aberdour S, Herrington C, Herman P, Rouchotas P, Lescheid D, Bradley R, Gignac T, Bernhardt B, Zhou Q, Guyatt G. Naturopathic medicine for the prevention of cardiovascular disease: a randomized clinical trial CMAJ. 2013 Jun 11;185(9):409-16 [28]
Herman PM, Szczurko O, Cooley K, Seely D A naturopathic approach to the prevention of cardiovascular disease: cost-effectiveness analysis of a pragmatic multi-worksite randomized clinical trial Journal of Occupational Environmental Medicine 2014 Feb;56(2):171-6 [29]
Kennedy DA, Hart J, Seely D. Cost Effectiveness of Natural Health Products: A Systematic Review of Randomized Clinical Trials. Evid Based Complement Alternat Med. 2009 September; 6(3): 297–304.[30]
Herman PM, Szczurko O, Cooley K, Mills EJ. Cost-effectiveness of naturopathic care for chronic low back pain. Alt Ther in Health and Med, 2008;14(2):32-9.[31]
Dugoua JJ, Seely D, Perri D, Cooley K, Forelli T, Mills E, Koren G. From type 2 diabetes to antioxidant activity: a systematic review of the safety and efficacy of common and cassia cinnamon bark. Can J of Phys & Pharm, 2007;85(9):837-47.[32]
Christopher Habib ND, Matthew Gowan ND, Stefan Podgrabinski, Tom Grodski ND, Brenda Leung ND, Maria Shapoval ND, Dugald Seely ND, MSc, Kieran Cooley Treating type 2 diabetes: A cross-sectional audit of naturopathic standards of care using the Naturopathic Patient Database Journal of Evidence-Based Complementary & Alternative Medicine April 2012;17(2):108-116 [33]
Deborah A. Kennedy, Kieran Cooley, Thomas R. Einarson, and Dugald Seely Objective Assessment of an Ionic Footbath (IonCleanse): Testing Its Ability to Remove Potentially Toxic Elements from the Body Journal of Environmental and Public Health: Volume 2012 [34]
Huff H, Cooley K, Waller N. Acupuncture for treatment of HIV associated acute inflammatory demyelinating polyradiculoneuropathy (Guillain-Barré syndrome) Medical Acupuncture, 2008;20(3):191-5.[35]
Mills E, Cooper C, Seely D, Kanfer I. African herbal medicines in the treatment of HIV: Hypoxis and Sutherlandia. An overview of evidence and pharmacology. Nutrition Journal, 2005;4(1):19.[36]
Leonard B, Huff H, Merryweather B, Lim A, Mills E. Knowledge of safety and herb-drug interations amongst HIV+ individuals: a focus group study. Can J Clin Pharm, 2004;11(2):e227-31.[37]
Mills EJ, Wu P, Seely D, Guyatt GH. Vitamin supplementation for prevention of mother-to-child transmission of HIV and pre-term delivery: a systematic review AIDS Res Ther. 2005;2(1):4.[38]
Seely D, Cooley K, Fritz H. Links between ADHD and Environmental Pollutants: Implications for Preventative Naturopathic Clinical Practice Townsend Letter for Doctors, 2009; Feb/Mar:83-88.[39]
Cooley K, Szczurko O, Perri D, Mills EJ, Bernhardt B, et. al. Naturopathic Care for Anxiety: A Randomized Controlled Trial ISRCTN78958974. PLoS One 2009;4(8):e6628.[40]
Prousky J, Hayman R. Orthomolecular and Botanical Treatments to Help Alleviate the Side Effects of Atypical Antipsychotic Drugs Journal of Ortho Med 2006;21(1):17-33.[41]
Prousky, J. Orthomolecular Treatment of Anxiety Disorders Townsend Letter for Doctors and Patients, 2005;259/260:82-87. [42]
Prousky JE. Pellagra may be a rare secondary complication of anorexia nervosa: a systematic review of the literature Altern Med Rev. 2003;8(2):180-5.[43]
Mills EJ, Chow TW. Randomized controlled trials in long-term care residents with dementia: a systematic review J Am Med Dir Assoc. 2003;4(6):302-7.[44]
Prousky J. Supplemental niacinamide mitigates anxiety symptoms: three case reports Journal of Ortho Med, 2005; 20(3):167-178.[45]
Prousky J. The Orthomolecular Treatment of Schizophrenia: A Primer for Clinicians Townsend Letter for Doctors, 2007;283:86-100.[46]
Prousky J Understanding the serum vitamin B12 level and its implications for treating neuropsychiatric conditions: an orthomolecular perspective Townsend Letter for Doctors & Patients, 2011;331/332:54-63.[47]
Szczurko O, Cooley K, Busse JW, Seely D, Bernhardt B, Guyatt GH, Zhou Q, Mills EJ. Naturopathic care for chronic low back pain: a randomized trial PLoS ONE, 2007;2(9):e919.[48]
Szczurko O, Cooley K, Mills EJ, Zhou Q, Perri D, Seely D. Naturopathic treatment of rotator cuff tendinitis among Canadian postal workers: A randomized controlled trial Arthritis Rheum 2009;61(8):1037-45.[49]
Seely D, Singh R. Adaptogenic potential of a polyherbal natural health product: report on a longitudinal clinical trial Evid Based Complement Alternat Med, 2007;4(3):375-80.[50]
Prousky J. Clinical Experiences with a Vitamin B3 Dependent Family J of Ortho Med, 2006; 21(4): 205-211.[51]
Kennedy D, Seely D Clinically based evidence of drug-herb interactions: a systematic review Expert Opinion Drug Safety

Citation: January 2010, Vol. 9, No. 1, Pages 79-124 ,[52]

Busse JW, Heaton G, Wu P, Wilson KR, Mills EJ. Disclosure of natural product use to primary care physicians: a cross-sectional survey of naturopathic clinic attendees Mayo Clin Proc, 2005;80(5):616-23.[53]
Prousky J. Double agent niacin-its beneficial effect upon the lipid profile, but its adverse effect upon plasma homocysteine: a case report Queen's Health Sciences Journal, 2006;8(1):34-38.[54]
Walji R, Wiktorowicz M. Governance of natural health products regulation: an iterative process Health Policy. 2013 Jun;111(1):86-94 [55]
Alonso-Coello P, Zhou Q, Martinez-Zapata MJ, Mills E, Heels-Ansdell D, Johanson JF, Guyatt G. Meta-analysis of flavonoids for the treatment of haemorrhoids Br J Surg. 2006;93(8):909-20.[56]
Mills E, Wilson K, Clarke M, Foster B, Walker S, Rachlis B, DeGroot N, Montori VM, Gold W, Phillips E, Myers S, Gallicano K. Milk thistle and indinavir: a randomized controlled pharmacokinetics study and meta-analysis Eur J Clin Pharmacol. 2005;61(1):1-7.[57]
Mills E, Wu P, Johnston BC, Gallicano K, Clarke M, Guyatt G. Natural health product-drug interactions: a systematic review of clinical trials Ther Drug Monit. 2005;27(5):549-57.[58]
Prousky J, Seely D. Randomized double blind, placebo-controlled pilot study assessing the ability of inositol hexaniacinate (hexanicotinate) to reduce symptoms of non-ulcer dyspepsia possibly due to insufficient hydrochloric acid production JOM. 2011. 26(1). 21-31 [59]
Hirschkorn K, Walji R, Boon H The role of natural health products (NHPs) in dietetic practice: results from a survey of Canadian dietitians BMC Complement Altern Med. 2013 Jul 3;13:156 [60]
Mills E, Prousky J, Raskin G, Gagnier J, Rachlis B, Montori VM, Juurlink D. The safety of over-the-counter niacin. A randomized placebo-controlled trial BMC Clin Pharmacol. 2003;3:4[61]
Prousky J, Seely D. The treatment of migraines and tension-type headaches with intravenous and oral niacin (nicotinic acid): literature review Nutrition Journal, 2005;4:3.[62]
Prousky, J. Understanding the Serum Vitamin B12 Level and its Implications for Treating Neuropsychiatric Conditions: An Orthomolecular Perspective Journal of Orthomolecular Medicine [63]
Prousky JE. Vitamin B12 (cobalamin) deficiency in elderly patients CMAJ, 2004;171(3):251-9.[64]
Prousky, J. E. Vitamin B3 for Depression: Case Report and Review of the Literature Journal of Orthomolecular Medicine, 2010; 25 (3): 137-147.[65]
Wilson K, Busse JW, Gilchrist A, Vohra S, Boon H, Mills E. Characteristics of Pediatric and Adolescent Patients Attending a Naturopathic College Clinic in Canada Pediatrics, 2005;115(3).[66]
Saunders PR, Smith F, Schusky RW. Echinacea purpurea (L.) in children: safety, tolerability, compliance, clin. effectiveness in upper respiratory tract infections Can J Physiol Pharmacol. 2007;85(11):1195-9.[67]
April KT, Walji R The state of research on complementary and alternative medicine in pediatric rheumatology Rheum Dis Clin North Am. 2011 Feb;37(1):85-94 [68]
Dugoua JJ, Seely D, Perri D, Koren G, Mills E. Safety and efficacy of black cohosh (Cimicifuga racemosa) during pregnancy and lactation Can J Clin Pharm, 2006;13(3):e257-61.[69]
Dugoua JJ, Perri D, Seely D, Mills E, Koren G. Safety and efficacy of blue cohosh (Caulophyllum thalictroides) during pregnancy and lactation. Can J Clin Pharm, 2008;15(1):e66-73.[70]
Dugoua JJ, Perri D, Seely D, Mills E, Koren G. Safety and efficacy of chastetree (Vitex agnus-castus) during pregnancy and lactation Can J Clin Pharm, 2008;15(1):e74-9.[71]
Dugoua JJ, Seely D, Perri D, Mills E, Koren G. Safety and efficacy of cranberry (vaccinium macrocarpon) during pregnancy and lactation Can J Clin Pharm, 2008;15(1):e80-6.[72]
Perri D, Dugoua JJ, Mills E, Koren G. Safety and efficacy of echinacea (Echinacea angustafolia, e. purpurea and e. pallida) during pregnancy and lactation Can J Clin Pharm, 2006;13(3):e262-7.[73]
Dugoua JJ, Mills E, Perri D, Koren G. Safety and efficacy of ginkgo (Ginkgo biloba) during pregnancy and lactation Can J Clin Pharm, 2006;13(3):e277-84.[74]
Seely D, Dugoua JJ, Perri D, Mills E, Koren G. Safety and efficacy of panax ginseng during pregnancy and lactation Can J Clin Pharm, 2008;15(1):e87-94.[75]
Dugoua JJ, Mills E, Perri D, Koren G. Safety and efficacy of St. John's wort (hypericum) during pregnancy and lactation Can J Clin Pharm, 2006;13(3):e268-76.[76]
Beales, J, Walji, R, Papoushek, C, Austin, Z. Exploring Professional Culture in the Context of Family Health Team Interprofessional Collaboration Health and Interprofessional Practice 1(1) [77]
Rishma Walji, Laura Weeks, Kieran Cooley, Dugald Seely Naturopathic medicine and aboriginal health: an exploratory study at Anishnawbe Health Toronto Can J Public Health 2010;101(5):475-80.[78]
Prousky J. The Treatment of Pulmonary Diseases and Respiratory-Related Conditions with Inhaled (Nebulized or Aerosolized) Glutathione eCAM, 2008;5(1):27-35.[79]
Brenda M. Y. Leung ND, MSc , Gillian Flower ND, BA , Kieran Cooley ND, MSc , Chris Habib ND, MSc , Matt Gowan ND , Stefan Podgrabinski , Dugald Seely ND, MSc Assessing the utility of an electronic research database to capture whole systems practice at two naturopathic outpatient teaching clinics Journal of Evidence-Based Complementary & Alternative Medicine, December 2012 [80]
Moher D, Weeks L, Ocampo M, Seely D, Sampson M, Altman DG, Schulz KF, Miller D, Simera I, Grimshaw J, Hoey J Describing reporting guidelines for health research: a systematic review J Clin Epidemiol. 2011 Jul;64(7):718-42 [81]
Mills EJ, Kelly S, Wu P, Guyatt GH Epidemiology and reporting of randomized trials employing re-randomization of patient groups Contemp Clin Trials. 2007;28(3):268-75 [82]
Leung B, Seely D. Guidelines to case report writing for naturopathic doctors. International Journal of Naturopathic Medicine. 2009 June;(4) 1:50-4.[83]
Ferreira-González I, Busse JW, Heels-Ansdell D, Montori VM, Akl EA, Bryant DM, Alonso-Coello P, Alonso J, Worster A, Upadhye S, Jaeschke R, Schünemann HJ, Permanyer-Miralda G, Pacheco-Huergo V, Domingo-Salvany A, Wu P, Mills EJ, Guyatt GH. Problems with use of composite end points in cardiovascular trials: a systematic review BMJ, 2007;334(7597):786.[84]
Mills EJ, Montori VM, Ross CP, Shea B, Wilson K, Guyatt GH. Systematically reviewing qualitative studies complements survey design: exploratory study of barriers to paediatric immunization J Clin Epidemiol, 2005;58(11):1101-8.[85]
Mills EJ, Wu P, Gagnier J, Devereaux PJ. The quality of randomized trial reporting in leading medical journals since the revised CONSORT statement Contemp Clin Trials, 2005;26(4):480-7.[86]
Jackson SF, Cleverly S, Poland B, Burman D, Edwards R, Robertson A. Working with Toronto neighbourhoods toward developing indicators of community capacity Health Promot. Internation., 2003;18(4):339-350.[87]
Mills EJ, Hollyer T, Guyatt G, Ross CP, Saranchuk R, Wilson K. A learning structure for clinical decision changes J Altern Complement Med. 2002;8(2):207-14.[88]
Wilson K, Mills EJ, Hollyer T, Vohra S, Guyatt G. 'A conceptual approach to causation-part 2 J Altern Complement Med. 2002;8(3):385-9.[89]
Wilson K, Mills EJ, Ross C, Guyatt G. Appraising the evidence for papers on therapy J Altern Complement Med. 2002;8(5):673-9.[90]
Wilson K, McGowan J, Guyatt G, Mills EJ. Asking the questions and identifying the information J Altern Complement Med. 2002;8(4):499-506.[91]
Wilson K, Mills EJ, McGowan J, Guyatt G. Interpreting the results of a study on therapy and applying them to a patient J Altern Complement Med. 2002;8(6):867-73.[92]
Wilson K, Mills EJ. Introducing evidence-based complementary and alternative medicine: answering the challenge J Altern Complement Med. 2002;8(2):103-5.[93]
Wilson K, Mills E, Ross C, McGowan J, Jadad A. 'Association of autistic spectrum disorder and the measles, mumps, and rubella vaccine: a systematic review' Arch Pediatr Adolesc Med, 2003;157(7):628-34.[94]
Wilson K, Mills EJ, Norman G, Tomlinson G. Changing attitudes towards polio vaccination Vaccine, 2005;23(23):3010-5.[95]
Main P, Leake J, Burman D. Oral Health Care in Canada – A View from the Trenches J Can Dental Assoc, 2006;72(4):319.[96]
Wu V, Huff H, Bhandari M. Pattern of Physical Injury Associated with Intimate Partner Violence in Women Presenting to the Emergency Department: A Systematic Review and Meta-Analysis Trauma, Violence, & Abuse Vol.11, No. 2, 71-82 (2010) DOI: 10.1177/1524838010367503.[97]
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