Ketogenic Diet

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Latest Edit: Hector 2014-03-13 (EDT)

See Also Naturopathic Therapies
See Also Clinical Nutrition


The ketogenic diet was developed in 1921 to help control seizures in children who failed to respond to anticonvulsant medications.[1] This diet forces the body to burn fats rather than carbohydrates.

Article The Ketogenic Diet, NDNR [1], 2012 January

Guidelines

The ketogenic diet involves:

  1. calorie-restricted diet with a fat to carbohydrate + protein ratio ranging from 2:1 to 5:1.
  2. restricted fluid intake

Uses

  • The ketogenic diet can be considered an option for children with intractable epilepsy who use multiple antiepileptic drugs. It is a treatment of choice for seizures associated with glucose transporter protein deficiency syndrome (ie, De Vivo disease) and pyruvate dehydrogenase complex deficiency.[1], [2]
  • The ketogenic diet may benefit a wide variety of neurological diseases, including epilepsy, headache, neurotrauma, Alzheimer disease, Parkinson disease, sleep disorders, brain cancer, autism, pain, and multiple sclerosis.[3]
  • A combined ketogenic, Mediterranean diet and one with phytoextracts and low carbohydrates/high-protein leads to weight reduction, improvements in cardiovascular risk markers and reduction in waist circumference.[4]

Cautions

  • Those undergoing the ketogenic diet must be monitor by a practitioner experienced in its use.
  • Initiation of the diet may cause vomiting, hypoglycemia, or dehydration.
  • Long-term problems may include moderate growth retardation, gallstones, acidosis or metabolic abnormalities, recurrent infections, hypercholesterolemia, hyperuricemia, vitamin deficiency, and feeding problems.
  • The ketogenic diet and anticonvulsant drugs have both been found to have an adverse effect on bone density.

References

  1. ↑ 1.0 1.1 Gaby, AR (2011) Nutritional Medicine. Fritz Perlberg Publishing.
  2. ↑ Rogovik AL, Goldman RD (Jun 2010) Ketogenic diet for treatment of epilepsy. Can Fam Physician.;56(6):540-2. PMID: 20547519.
  3. ↑ Stafstrom CE, Rho JM (2012) The ketogenic diet as a treatment paradigm for diverse neurological disorders. Front Pharmacol.;3:59. PMID: 22509165.
  4. ↑ Paoli A, Cenci L, Grimaldi KA (Oct 2011) Effect of ketogenic Mediterranean diet with phytoextracts and low carbohydrates/high-protein meals on weight, cardiovascular risk factors, body composition and diet compliance in Italian council employees. Nutr J.;10:112. PMID: 21992535.